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Structural determinants of the alpha2 adrenoceptor subtype selectivity

Alpha2-adrenergic receptor (α2-AR) subtypes, acting mainly on the central nervous and cardiovascular systems, represent important targets for drug design, confirmed by the high number of studies published so far. Presently, only few α2-AR subtype selective compounds are known. Using homology modelin...

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Bibliografiske detaljer
Main Authors: Ostopovici-Halip, Liliana, Curpăn, Ramona, Mracec, Maria, Bologa, Cristian G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307019/
https://ncbi.nlm.nih.gov/pubmed/21602069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2011.04.011
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