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Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid.

Block condensation of MePOCI2 or MeP(NEt2)2 with appropriately protected tetra(thymidine methanephosphonates) of predetermined sense of chirality at asymmetric phosphonate centres gave two pairs of diastereomeric mixtures, namely (SpSpSpSpSpSpSp + SpSpSpRpSpSpSp) 5a and (RpRpRpRpRpRpRp + RpRpRpSpRpR...

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Bibliografske podrobnosti
Main Authors: Lesnikowski, Z J, Jaworska, M, Stec, W J
Format: Artigo
Jezik:Inglês
Izdano: 1990
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC330690/
https://ncbi.nlm.nih.gov/pubmed/2336391
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