Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

In neonatal mouse skin, two types of dermal papilla (DP) are distinguished by Sox2 expression: CD133+Sox2+ DP are associated with guard/awl/auchene hairs, whereas CD133+Sox2− DP are associated with zigzag (ZZ) hairs. We describe a three-dimensional hydrogel culture system that supports clonal growth...

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Main Authors: Driskell, Ryan R, Juneja, Vikram R, Connelly, John T, Kretzschmar, Kai, Tan, David W -M, Watt, Fiona M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306894/
https://ncbi.nlm.nih.gov/pubmed/22189784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2011.428
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