Levels of Neural Progenitors in the Hippocampus Predict Memory Impairment and Relapse to Drug Seeking as a Function of Excessive Methamphetamine Self-Administration

Methamphetamine affects the hippocampus, a brain region crucial for learning and memory, as well as relapse to drug seeking. Rats self-administered methamphetamine for 1 h twice weekly (intermittent-short-I-ShA), 1 h daily (limited-short-ShA), or 6 h daily (extended-long-LgA) for 22 sessions. After...

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Detalhes bibliográficos
Main Authors: Recinto, Patrick, Samant, Anjali Rose H, Chavez, Gustavo, Kim, Airee, Yuan, Clara J, Soleiman, Matthew, Grant, Yanabel, Edwards, Scott, Wee, Sunmee, Koob, George F, George, Olivier, Mandyam, Chitra D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306889/
https://ncbi.nlm.nih.gov/pubmed/22205547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.315
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