Backbone-modified oligonucleotides containing a butanediol-1,3 moiety as a 'vicarious segment' for the deoxyribosyl moiety--synthesis and enzyme studies.

Sequential single replacement of nucleosides within the decanucleotide d[GGGAATTCCC] (7) by means of a butanediol-1,3 residue allowed us to obtain a set of ten decanucleotides containing 'vicarious' (V) carbon-phosphate fragments. These analogues were further used as substrates for svPDE,...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Wilk, A, Koziolkiewicz, M, Grajkowski, A, Uznanski, B, Stec, W J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1990
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330684/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.8.2065
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires