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Bevacizumab Reduces the Growth Rate Constants of Renal Carcinomas: A Novel Algorithm Suggests Early Discontinuation of Bevacizumab Resulted in a Lack of Survival Advantage
BACKGROUND: To hasten cancer drug development, new paradigms are needed to assess therapeutic efficacy. In a randomized phase II study in patients with renal cell carcinoma, 10 μg/kg bevacizumab (Avastin(®); Genentech, Inc., South San Francisco, CA) administered every 2 weeks resulted in a longer ti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306833/ https://ncbi.nlm.nih.gov/pubmed/18827177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2008-0016 |
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