Risk-Reducing Salpingo-Oophorectomy for the Prevention of BRCA1- and BRCA2-Associated Breast and Gynecologic Cancer: A Multicenter, Prospective Study

PURPOSE: Risk-reducing salpingo-oophorectomy (RRSO) has been widely adopted as a key component of breast and gynecologic cancer risk-reduction for women with BRCA1 and BRCA2 mutations. Despite 17% to 39% of all BRCA mutation carriers having a mutation in BRCA2, no prospective study to date has evalu...

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Главные авторы: Kauff, Noah D., Domchek, Susan M., Friebel, Tara M., Robson, Mark E., Lee, Johanna, Garber, Judy E., Isaacs, Claudine, Evans, D. Gareth, Lynch, Henry, Eeles, Rosalind A., Neuhausen, Susan L., Daly, Mary B., Matloff, Ellen, Blum, Joanne L., Sabbatini, Paul, Barakat, Richard R., Hudis, Clifford, Norton, Larry, Offit, Kenneth, Rebbeck, Timothy R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306809/
https://ncbi.nlm.nih.gov/pubmed/18268356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.13.9626
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