Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma

Gene amplification is a tumor-specific event during malignant transformation. Recent studies have proposed a lineage-dependency (addiction) model of human cancer whereby amplification of certain lineage transcription factors predisposes a survival mechanism in tumor cells. These tumor cells are deri...

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Detalhes bibliográficos
Main Authors: Lin, Lin, Bass, Adam J., Lockwood, William W., Wang, Zhuwen, Silvers, Amy L., Thomas, Dafydd G., Chang, Andrew C., Lin, Jules, Orringer, Mark B., Li, Weiquan, Glover, Thomas W., Giordano, Thomas J., Lam, Wan L., Meyerson, Matthew, Beer, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306720/
https://ncbi.nlm.nih.gov/pubmed/22375031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011989109
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