Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography

Ebola virus is a highly pathogenic filovirus causing severe hemorrhagic fever with high mortality rates. It assembles heterogenous, filamentous, enveloped virus particles containing a negative-sense, single-stranded RNA genome packaged within a helical nucleocapsid (NC). We have used cryo-electron m...

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Main Authors: Bharat, Tanmay A. M., Noda, Takeshi, Riches, James D., Kraehling, Verena, Kolesnikova, Larissa, Becker, Stephan, Kawaoka, Yoshihiro, Briggs, John A. G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306676/
https://ncbi.nlm.nih.gov/pubmed/22371572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120453109
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