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BMK1 kinase suppresses epithelial-mesenchymal transition through the Akt/GSK3β signaling pathway
Epithelial-mesenchymal transition (EMT) plays a crucial role in the development of cancer metastasis. The MAP kinases ERK, JNK and p38 have been implicated in promoting EMT, but a role for the MAP kinase BMK1 has not been studied. Here we report that BMK1 signaling suppresses EMT. BMK1 elevation aug...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306490/ https://ncbi.nlm.nih.gov/pubmed/22282661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2055 |
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