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Three Ring Posttranslational Circuses: Insertion of Oxazoles, Thiazoles, and Pyridines into Protein-Derived Frameworks

Nitrogen heterocycles are the key functional and structural elements in both RNA and DNA, in half a dozen of the most important coenzymes, and in many synthetic drug scaffolds. On the other hand, only three of twenty proteinogenic amino acids have nitrogen heterocycles: proline, histidine and trypto...

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Detalhes bibliográficos
Main Authors: Walsh, Christopher T., Malcolmson, Steven J., Young, Travis S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306484/
https://ncbi.nlm.nih.gov/pubmed/22206579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200518n
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