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Dehydrative Fragmentation of 5-Hydroxyalkyl-1H-tetrazoles: A Mild Route to Alkylidenecarbenes

[Image: see text] The development of a mild, base-free method for the generation of alkylidenecarbenes is reported. Treatment of 5-hydroxyalkyl-1 H-tetrazoles with carbodiimides generates products arising from the 1,2-rearrangement or [1,5]-C-H bond insertion of a putative alkylidenecarbene. Formati...

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Detalhes bibliográficos
Main Authors: Wardrop, Duncan J., Komenda, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306463/
https://ncbi.nlm.nih.gov/pubmed/22372676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300276p
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