Variants Located Upstream of CHRNB4 on Chromosome 15q25.1 Are Associated with Age at Onset of Daily Smoking and Habitual Smoking

Several genome-wide association and candidate gene studies have linked chromosome 15q24–q25.1 (a region including the CHRNA5-CHRNA3-CHRNB4 gene cluster) with alcohol dependence, nicotine dependence and smoking-related illnesses such as lung cancer and chronic obstructive pulmonary disease. To furthe...

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Bibliografiska uppgifter
Huvudupphovsmän: Kapoor, Manav, Wang, Jen-Chyong, Bertelsen, Sarah, Bucholz, Kathy, Budde, John P., Hinrichs, Anthony, Agrawal, Arpana, Brooks, Andrew, Chorlian, David, Dick, Danielle, Hesselbrock, Victor, Foroud, Tatiana, Kramer, John, Kuperman, Samuel, Manz, Niklas, Nurnberger, John, Porjesz, Bernice, Rice, John, Tischfield, Jay, Xuei, Xiaoling, Schuckit, Marc, Edenberg, Howard J., Bierut, Laura J., Goate, Alison M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306405/
https://ncbi.nlm.nih.gov/pubmed/22438940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033513
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