GlmS and NagB Regulate Amino Sugar Metabolism in Opposing Directions and Affect Streptococcus mutans Virulence

Streptococcus mutans is a cariogenic pathogen that produces an extracellular polysaccharide (glucan) from dietary sugars, which allows it to establish a reproductive niche and secrete acids that degrade tooth enamel. While two enzymes (GlmS and NagB) are known to be key factors affecting the entranc...

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Auteurs principaux: Kawada-Matsuo, Miki, Mazda, Yusuke, Oogai, Yuichi, Kajiya, Mikihito, Kawai, Toshihisa, Yamada, Sakuo, Miyawaki, Shouichi, Oho, Takahiko, Komatsuzawa, Hitoshi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306399/
https://ncbi.nlm.nih.gov/pubmed/22438919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033382
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