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Regulation of p130(Cas)/BCAR1 Expression in Tamoxifen-Sensitive and Tamoxifen-Resistant Breast Cancer Cells by EGR1 and NAB2

Elevated levels of p130(Cas)/BCAR1 (Crk-associated substrate/breast cancer antiestrogen resistance 1) are found in aggressive breast tumors and are associated with tamoxifen resistance of mammary cancers. p130(Cas) promotes the integration of protein complexes involved in multiple signaling pathways...

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Main Authors: Kumbrink, Joerg, Kirsch, Kathrin H
格式: Artigo
語言:Inglês
出版: Neoplasia Press Inc. 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306256/
https://ncbi.nlm.nih.gov/pubmed/22431919
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