Targeting atrioventricular differences in ion channel properties for terminating acute atrial fibrillation in pigs

AIMS: The goal was to terminate atrial fibrillation (AF) by targeting atrioventricular differences in ionic properties. METHODS AND RESULTS: Optical mapping was used to record electrical activity during carbachol (0.25–0.5 μM)-induced AF in pig hearts. The atrial-specific current, I(Kur), was blocke...

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Hlavní autoři: Pandit, Sandeep V., Zlochiver, Sharon, Filgueiras-Rama, David, Mironov, Sergey, Yamazaki, Masatoshi, Ennis, Steven R., Noujaim, Sami F., Workman, Antony J., Berenfeld, Omer, Kalifa, Jerome, Jalife, José
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Original Articles: Focus on the Molecular Basis of Atrial Fibrillation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306132/
https://ncbi.nlm.nih.gov/pubmed/21076156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq359
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