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Resistance of Sézary Cells to TNF-α-Induced Apoptosis Is Mediated in Part by a Loss of TNFR1 and a High Level of the IER3 Expression
Failure to execute an apoptotic program is one of the critical steps and a common mechanism promoting tumorogenesis. Immediate early responsive gene 3 (IER3) has been shown to be upregulated in several cancers. IER3 is a stress induced gene, which upregulation leads to reduction in production of rea...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306129/ https://ncbi.nlm.nih.gov/pubmed/22417305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0625.2012.01452.x |
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