The primary structure and expression of the second open reading frame of the polymerase gene of the coronavirus MHV-A59; a highly conserved polymerase is expressed by an efficient ribosomal frameshifting mechanism.

Sequence analysis of a substantial part of the polymerase gene of the murine coronavirus MHV-A59 revealed the 3' end of an open reading frame (ORF1a) overlapping with a large ORF (ORF1b; 2733 amino acids) which covers the 3' half of the polymerase gene. The expression of ORF1b occurs by a...

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Main Authors: Bredenbeek, P J, Pachuk, C J, Noten, A F, Charité, J, Luytjes, W, Weiss, S R, Spaan, W J
Formato: Artigo
Idioma:Inglês
Publicado: 1990
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC330602/
https://ncbi.nlm.nih.gov/pubmed/2159623
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