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A role for O-GlcNAcylation in setting circadian clock speed

Post-translational modifications of one or more central “clock” proteins, most notably time-of-day-dependent changes in phosphorylation, are critical for setting the pace of circadian (≅24 h) clocks. In animals, PERIOD (PER) proteins are the key state variable regulating circadian clock speed and un...

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Bibliografische gegevens
Hoofdauteurs: Kim, Eun Young, Jeong, Eun Hee, Park, Sujin, Jeong, Hyun-Jeong, Edery, Isaac, Cho, Jin Won
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305986/
https://ncbi.nlm.nih.gov/pubmed/22327476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.182378.111
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