THROMBOLYTIC EFFICACY OF TISSUE PLASMINOGEN ACTIVATOR-LOADED ECHOGENIC LIPOSOMES IN A RABBIT THROMBUS MODEL

INTRODUCTION: Ultrasound (US)-enhanced thrombolytic treatment protocols currently in clinical trials for stroke applications involve systemic administration of tissue plasminogen activator (tPA; Alteplase), which carries a risk of adverse bleeding events. The present study aimed to compare the throm...

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Autors principals: Laing, Susan T., Moody, Melanie R., Kim, Hyunggun, Smulevitz, Beverly, Huang, Shao-Ling, Holland, Christy K., McPherson, David D., Klegerman, Melvin E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305817/
https://ncbi.nlm.nih.gov/pubmed/22133272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2011.11.010
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