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Reference genome-independent assessment of mutation density using restriction enzyme-phased sequencing
BACKGROUND: The availability of low cost sequencing has spurred its application to discovery and typing of variation, including variation induced by mutagenesis. Mutation discovery is challenging as it requires a substantial amount of sequencing and analysis to detect very rare changes and distingui...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305632/ https://ncbi.nlm.nih.gov/pubmed/22333298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-72 |
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