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Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants

Candida albicans is a major life-threatening human fungal pathogen. Host defence against systemic Candida infection relies mainly on phagocytosis of fungal cells by cells of the innate immune system. In this study, we have employed video microscopy, coupled with sophisticated image analysis tools, t...

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Bibliographic Details
Main Authors: Lewis, Leanne E., Bain, Judith M., Lowes, Christina, Gillespie, Collette, Rudkin, Fiona M., Gow, Neil A. R., Erwig, Lars-Peter
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305454/
https://ncbi.nlm.nih.gov/pubmed/22438806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002578
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