A Splice Site Variant in the Bovine RNF11 Gene Compromises Growth and Regulation of the Inflammatory Response

We report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle (BBC). By resequencing positional candidates, we identify the causative c124-2A>G splice variant in intron 1 of the RNF11 gene, for which all affected animals a...

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Detalhes bibliográficos
Main Authors: Sartelet, Arnaud, Druet, Tom, Michaux, Charles, Fasquelle, Corinne, Géron, Sarah, Tamma, Nico, Zhang, Zhiyan, Coppieters, Wouter, Georges, Michel, Charlier, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305398/
https://ncbi.nlm.nih.gov/pubmed/22438830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002581
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