Afadin, A Ras/Rap Effector That Controls Cadherin Function, Promotes Spine and Excitatory Synapse Density in the Hippocampus

Many molecules regulate synaptogenesis, but intracellular signaling pathways required for their functions are poorly understood. Afadin is a Rap-regulated, actin-binding protein that promotes cadherin complex assembly as well as binding many other cell adhesion molecules and receptors. To examine it...

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Main Authors: Beaudoin, Gerard M. J., Schofield, Claude M., Nuwal, Tulip, Zang, Keling, Ullian, Erik M., Huang, Bo, Reichardt, Louis F.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305287/
https://ncbi.nlm.nih.gov/pubmed/22219273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4565-11.2012
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