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The George E. Brown Lecture: The Interplay Between Heart And Skeletal Muscle Disease In Heart Failure

The study of single gene disorders often provides insight for more complex human disease. Mutations in the genes encoding the dystrophin protein complex cause muscular dystrophy and cardiomyopathy by destabilizing the plasma membrane of skeletal myofibers and cardiomyocytes. In these diseases, progr...

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Main Authors: McNally, Elizabeth M., Goldstein, Jeffery A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305258/
https://ncbi.nlm.nih.gov/pubmed/22383709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.256776
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