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Tumor growth is suppressed in mice expressing a truncated XRCC1 protein

Tumor progression depends on the support of cells in the microenvironment, and is driven in part by the generation of reactive oxygen species (ROS). ROS can damage DNA, and the repair of damaged DNA is a well-known process involved in tumor initiation and promotion, but the role of DNA repair in tum...

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Detalhes bibliográficos
Main Authors: Pettan-Brewer, Christina, Morton, John, Cullen, Sarah, Enns, Linda, Kehrli, Keffy RM, Sidorova, Julia, Goh, Jorming, Coil, Rebecca, Ladiges, Warren C
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304571/
https://ncbi.nlm.nih.gov/pubmed/22432057
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