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Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology

Bone strength is influenced by many properties intrinsic to bone, including its mass, geometry, and mineralization. To further advance our understanding of the genetic basis of bone strength-related traits, we utilized a large (N=815), moderately (G(4)) advanced intercross line (AIL) of mice derived...

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Detalhes bibliográficos
Main Authors: Farber, Charles R., Kelly, Scott A., Baruch, Ethan, Yu, Daniel, Hua, Kunjie, Nehrenberg, Derrick L., Pardo-Manuel de Villena, Fernando, Buus, Ryan J., Garland, Theodore, Pomp, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304441/
https://ncbi.nlm.nih.gov/pubmed/21638317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.436
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