Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum

BACKGROUND: To evaluate the activity and safety of everolimus and identify potential biomarkers for efficacy of everolimus in patients with advanced gastric cancer (AGC), who failed both fluoropyrimidine and platinum. METHODS: Fifty-four patients received everolimus (10 mg day(−1)). The primary obje...

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Detalhes bibliográficos
Main Authors: Yoon, D H, Ryu, M-H, Park, Y S, Lee, H J, Lee, C, Ryoo, B-Y, Lee, J-L, Chang, H-M, Kim, T W, Kang, Y-K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304416/
https://ncbi.nlm.nih.gov/pubmed/22343617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.47
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