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Primary WWOX phosphorylation and JNK activation during etoposide induces cytotoxicity in HEK293 cells

BACKGROUND AND THE PURPOSE OF THE STUDY: Etoposide is an antineoplastic agent used in multiple cancers. It is known that etoposide induce cell death via interaction with topoisomerase II; however, the etopoisde cellular response is poorly understood. Upon etoposide induced DNA damage, many stress si...

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Bibliografische gegevens
Hoofdauteurs: Jamshidiha, M., Habibollahi, P., Ostad, S.N., Ghahremani, M.H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Tehran University of Medical Sciences 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304374/
https://ncbi.nlm.nih.gov/pubmed/22615609
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