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Preparation and characterization of superporous hydrogels as gastroretentive drug delivery system for rosiglitazone maleate

BACKGROUND AND THE PURPOSE OF THE STUDY: Many drugs which have narrow therapeutic window and are absorbed mainly in stomach have been developed as gastroretentive delivery system. Rosiglitazone maleate, an anti-diabetic, is highly unstable at basic pH and is extensively absorbed from the stomach. He...

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Bibliografiske detaljer
Main Authors: Vishal Gupta, N., Shivakumar, H.G.
Format: Artigo
Sprog:Inglês
Udgivet: Tehran University of Medical Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304361/
https://ncbi.nlm.nih.gov/pubmed/22615618
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