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The mRNA-binding protein which controls ferritin and transferrin receptor expression is conserved during evolution.

A post-transcriptional regulatory protein, termed iron regulatory factor (IRF), that binds specifically to the iron-responsive elements of ferritin and transferrin receptor mRNA, has recently been identified in the cytoplasm of human and mouse cells. Activation of this factor by low intracellular ir...

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Detalhes bibliográficos
Main Authors: Rothenberger, S, Müllner, E W, Kühn, L C
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC330432/
https://ncbi.nlm.nih.gov/pubmed/2157191
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