Toll-Like Receptor-4 Mediates Intestinal Barrier Breakdown after Thermal Injury

OBJECTIVE: Toll-like receptor 4 (TLR-4) activation after sterile injury leads to organ dysfunction at distant sites. We have shown previously that intestinal barrier breakdown and alteration of tight junction proteins follows thermal injury; however, the role of TLR-4 in this process remains unclear...

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Autors principals: Peterson, Carrie Y., Costantini, Todd W., Loomis, William H., Putnam, James G., Wolf, Paul, Bansal, Vishal, Eliceiri, Brian P., Baird, Andrew, Coimbra, Raul
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Articles from the Surgical Infection Society Meetings
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304242/
https://ncbi.nlm.nih.gov/pubmed/20374005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/sur.2009.053
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