Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea

AIMS: Delayed lipoprotein clearance is associated with atherosclerosis. This study examined whether chronic intermittent hypoxia (CIH), a hallmark of obstructive sleep apnoea (OSA), can lead to hyperlipidaemia by inhibiting clearance of triglyceride rich lipoproteins (TRLP). METHODS AND RESULTS: Mal...

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Detalhes bibliográficos
Main Authors: Drager, Luciano F., Li, Jianguo, Shin, Mi-Kyung, Reinke, Christian, Aggarwal, Neil R., Jun, Jonathan C., Bevans-Fonti, Shannon, Sztalryd, Carole, O'Byrne, Sheila M., Kroupa, Olessia, Olivecrona, Gunilla, Blaner, William S., Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303712/
https://ncbi.nlm.nih.gov/pubmed/21478490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehr097
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