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Atomistic basis for the on–off signaling mechanism in SAM-II riboswitch

Many bacterial genes are controlled by metabolite sensing motifs known as riboswitches, normally located in the 5′ un-translated region of their mRNAs. Small molecular metabolites bind to the aptamer domain of riboswitches with amazing specificity, modulating gene regulation in a feedback loop as a...

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Main Authors: Kelley, Jennifer Munro, Hamelberg, Donald
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303485/
https://ncbi.nlm.nih.gov/pubmed/19969538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1106
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