β(3)-Adrenoceptor Antagonist SR59230A Attenuates the Imbalance of Systemic and Myocardial Oxygen Transport Induced by Dopamine in Newborn Lambs

BACKGROUND: In neonates, the increase in O(2)-delivery (DO(2)) by dopamine is offset by a greater increase in O(2)-consumption (VO(2)). This has been attributed to β(3)-adrenergic receptors in neonatal brown fat tissue. β(3) receptors in the heart have negative inotropic properties. We evaluated the...

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Detalhes bibliográficos
Main Authors: Gill, Richdeep S., Cheung, Po-Yin, Yu, Xiaoyang, Aklabi, Mohammed Al, Nagendran, Jeevan, Quinonez, Luis G., Li, Ying Qian, Miller, John, Ross, David B., Rebeyka, Ivan M., Li, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303209/
https://ncbi.nlm.nih.gov/pubmed/22442641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMC.S8654
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