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A theoretical investigation of the base sequence preferences of monointercalating polymethylene carboxamide derivatives 9-aminoacridine.

Theoretical computations are performed of the comparative binding affinities of five polymethylene carboxamide derivatives of 9-aminoacridine to a series of double-stranded hexanucleotides. The purpose of this investigation is to ascertain whether minor groove recognition of a guanine base adjacent...

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Bibliografiske detaljer
Main Authors: Coulombeau, C, Gresh, N
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC330317/
https://ncbi.nlm.nih.gov/pubmed/2315037
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