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Mitochondrial function, inflammation, fat and bone in HIV lipoatrophy: randomized study of uridine supplementation or switch to tenofovir

BACKGROUND: Lipoatrophy modestly improves when the thymidine analogue nucleoside reverse transcriptase inhibitor (tNRTI) is removed. In vitro, uridine (NucleomaxX (®); Pharma Nord, Vojens, Denmark) reversed tNRTI mitochondrial toxicity. METHODS: All patients had lipoatrophy on a tNRTI-containing reg...

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Autors principals: McComsey, Grace A, O’Riordan, MaryAnn, Choi, Julia, Libutti, Daniel, Rowe, David, Storer, Norma, Harrill, Danielle, Gerschenson, Mariana
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302940/
https://ncbi.nlm.nih.gov/pubmed/22293126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1928
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