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NECDIN-E2F4 INTERACTION PROVIDES INSULIN-SENSITIZING EFFECT AFTER WEIGHT LOSS INDUCED BY GASTRIC BYPASS SURGERY
BACKGROUND: The insulin/ growth factor 1 (IGF-1) signaling pathway promotes adipocyte differentiation and therefore insulin sensitivity via suppression of Necdin expression, which represses PPAR γ promoter activity via interaction with E2F4 in mouse adipocytes. OBJECTIVES: The aim of this study was...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302937/ https://ncbi.nlm.nih.gov/pubmed/22138333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.soard.2011.10.014 |
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