Pre-Clinical Evaluation of a (213)Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication

BACKGROUND: Any strategy for curing HIV infection must include a method to eliminate viral-infected cells. Based on our earlier proof-of-principle results targeting HIV-1 infected cells with radiolabeled antibody (mAb) to gp41 viral antigen, we embarked on identifying a suitable candidate mAb for pr...

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Hlavní autoři: Dadachova, Ekaterina, Kitchen, Scott G., Bristol, Gregory, Baldwin, Gayle Cocita, Revskaya, Ekaterina, Empig, Cyril, Thornton, George B., Gorny, Miroslaw K., Zolla-Pazner, Susan, Casadevall, Arturo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302885/
https://ncbi.nlm.nih.gov/pubmed/22427811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031866
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