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Uncovering the Molecular Machinery of the Human Spindle—An Integration of Wet and Dry Systems Biology

The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments. However, because of its dynamic organization and complex regulation it is diffic...

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Bibliographische Detailangaben
Hauptverfasser: Rojas, Ana M., Santamaria, Anna, Malik, Rainer, Jensen, Thomas Skøt, Körner, Roman, Morilla, Ian, de Juan, David, Krallinger, Martin, Hansen, Daniel Aaen, Hoffmann, Robert, Lees, Jonathan, Reid, Adam, Yeats, Corin, Wehner, Anja, Elowe, Sabine, Clegg, Andrew B., Brunak, Søren, Nigg, Erich A., Orengo, Christine, Valencia, Alfonso, Ranea, Juan A. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302876/
https://ncbi.nlm.nih.gov/pubmed/22427808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031813
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