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Non-Enzymatic Decomposition of Collagen Fibers by a Biglycan Antibody and a Plausible Mechanism for Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory and destructive joint disorder that affects tens of millions of people worldwide. Normal healthy joints maintain a balance between the synthesis of extracellular matrix (ECM) molecules and the proteolytic degradation of damaged ones. In...

詳細記述

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書誌詳細
主要な著者: Antipova, Olga, Orgel, Joseph P. R. O.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302792/
https://ncbi.nlm.nih.gov/pubmed/22427827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032241
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