Approaches to localizing disease genes as applied to cystic fibrosis.

Using chromosome jumping and walking and restriction fragment length polymorphism (RFLP) analysis, we have defined the region which must contain the cystic fibrosis gene. DNA segments spanning approximately 250 kb in the direction of the gene were isolated and used to identify several new polymorphi...

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Publicado en:Nucleic Acids Res
Autores principales: Dean, M, Drumm, M L, Stewart, C, Gerrard, B, Perry, A, Hidaka, N, Cole, J L, Collins, F S, Iannuzzi, M C
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1990
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1970161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.2.345
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