Pharmacokinetics of Ampicillin/Sulbactam in Critically Ill Patients with Acute Kidney Injury undergoing Extended Dialysis

BACKGROUND AND OBJECTIVES: The fixed antibacterial combination of ampicillin and sulbactam is frequently used for various infections. Intact kidneys eliminate approximately 71% of ampicillin and 78% of sulbactam. Patients on thrice-weekly low-flux hemodialysis exhibit an ampicillin t(1/2) of 2.3 hou...

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Bibliographic Details
Main Authors: Lorenzen, Johan M., Broll, Michael, Kaever, Volkhard, Burhenne, Heike, Hafer, Carsten, Clajus, Christian, Knitsch, Wolfgang, Burkhardt, Olaf, Kielstein, Jan T.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302675/
https://ncbi.nlm.nih.gov/pubmed/22223613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05690611
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