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Synaptic Adaptations in the Nucleus Accumbens Caused by Experiences Linked to Relapse

BACKGROUND: Excitatory synaptic transmission in the nucleus accumbens (NAc) regulates the reinstatement of drug-seeking, an animal model of relapse in human drug addicts. However, the functional adaptations at NAc synapses that mediate reinstatement are not clearly understood. METHODS: We assessed t...

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Autores principales: Rothwell, Patrick E., Kourrich, Saïd, Thomas, Mark J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302659/
https://ncbi.nlm.nih.gov/pubmed/21329910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.12.028
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