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SARS-CoV heptad repeat 2 is a trimer of parallel helices

In severe acute respiratory syndrome coronavirus, the envelope heptad repeat 2 (HR2) plays a critical role in viral entry. Moreover, HR2 is both the target for novel antiviral therapies and, as an isolated peptide, presents a potential antiviral therapeutic. The structure of HR2, as determined by NM...

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Библиографические подробности
Главные авторы: Celigoy, Jessica, Ramirez, Benjamin, Caffrey, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley Subscription Services, Inc., A Wiley Company 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302656/
https://ncbi.nlm.nih.gov/pubmed/21922588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.736
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