Automated Discovery and Quantification of Image-Based Complex Phenotypes: A Twin Study of Drusen Phenotypes in Age-Related Macular Degeneration

PURPOSE. Determining the relationships between phenotype and genotype of many disorders can improve clinical diagnoses, identify disease mechanisms, and enhance therapy. Most genetic disorders result from interaction of many genes that obscure the discovery of such relationships. The hypothesis for...

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Hauptverfasser: Quellec, Gwenole, Russell, Stephen R., Seddon, Johanna M., Reynolds, Robyn, Scheetz, Todd, Mahajan, Vinit B., Stone, Edwin M., Abràmoff, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302481/
https://ncbi.nlm.nih.gov/pubmed/22039249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6793
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