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Characterization of the RNA Silencing Suppression Activity of the Ebola Virus VP35 Protein in Plants and Mammalian Cells

Ebola virus (EBOV) causes a lethal hemorrhagic fever for which there is no approved effective treatment or prevention strategy. EBOV VP35 is a virulence factor that blocks innate antiviral host responses, including the induction of and response to alpha/beta interferon. VP35 is also an RNA silencing...

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Autori principali: Zhu, Yali, Cherukuri, Nil Celebi, Jackel, Jamie N., Wu, Zetang, Crary, Monica, Buckley, Kenneth J., Bisaro, David M., Parris, Deborah S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302343/
https://ncbi.nlm.nih.gov/pubmed/22238300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05741-11
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