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Bovine Herpesvirus Type 4 Glycoprotein L Is Nonessential for Infectivity but Triggers Virion Endocytosis during Entry

The core entry machinery of mammalian herpesviruses comprises glycoprotein B (gB), gH, and gL. gH and gL form a heterodimer with a central role in viral membrane fusion. When archetypal alpha- or betaherpesviruses lack gL, gH misfolds and progeny virions are noninfectious. However, the gL of the rha...

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Detalhes bibliográficos
Main Authors: Lété, Céline, Machiels, Bénédicte, Stevenson, Philip G., Vanderplasschen, Alain, Gillet, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302276/
https://ncbi.nlm.nih.gov/pubmed/22205754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06238-11
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