Somatic Mutations in the Notch, NF-KB, PIK3CA, and Hedgehog Pathways in Human Breast Cancers

Exome sequencing of human breast cancers has revealed a substantial number of candidate cancer genes with recurring but infrequent somatic mutations. To determine more accurately their mutation prevalence, we performed a mutation analysis of 36 novel candidate cancer genes in 96 human breast cancers...

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Autores principales: Jiao, Xiang, Wood, Laura, Lindman, Monica, Jones, Sian, Buckhaults, Phillip, Polyak, Kornelia, Sukumar, Saraswati, Carter, Hannah, Kim, Dewey, Karchin, Rachel, Sjöblom, Tobias
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302210/
https://ncbi.nlm.nih.gov/pubmed/22302350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21935
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