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SUMOylation of the Transcriptional Corepressor KAP1 is Regulated by the Serine and Threonine Phosphatase PP1

KRAB domain–associated protein 1 (KAP1, also known as TIF1β) is a universal transcriptional corepressor that is susceptible to phosphorylation at Ser(824) by ataxia-telangiectasia mutated (ATM) and to modification by small ubiquitin-like modifying (SUMO) proteins. Here, we found that whereas protein...

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Autori principali: Li, Xu, Lin, H. Helen, Chen, Hanqing, Xu, Xingzhi, Shih, Hsiu-Ming, Ann, David K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302164/
https://ncbi.nlm.nih.gov/pubmed/20424263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000781
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